Apixaban, sold under the trade name Eliquis among others, is an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with atrial fibrillation. Specifically Apixaban used to prevent blood clots following hip or knee replacement and in those with a history of prior clots. It is used as an alternative to warfarin and does not require monitoring by blood tests.It is taken by mouth.

Common side effects include bleeding and nausea.Other side effects may include bleeding around the spine and allergic reactions.Use is not recommended during pregnancy or breastfeeding.Use appears to be relatively safe in those with mild kidney problems.Compared to warfarin it has fewer interactions with other medications. It is a direct factor Xa inhibitor.

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