EVISTA

19 Aug 2019

Generic Name : RALOXIFENE

ABSTRACT –

Evista is a medication drug that is used to treat osteoporosis and prevent invasive breast cancer in post-menopausal women. This drug is classified as a selective estrogen receptor modulator that influences the manner in which bone formation/breakdown occurs in the body, thus reducing the rate at which bone tissue loss (osteoporosis) occurs. Evista is also an antineoplastic agent.

DOSAGE –

  • Evista is to be taken as directed by the doctors. Consume this drug only as prescribed to avoid overdose or other harmful effects.
  • This drug is to be taken at the same time every day with/without food.
  • General Adult Dosage available:
  • Oral – 60mg per day

SIDE EFFECTS –

  • Cramps in the leg
  • Swelling in the limbs
  • Hot flashes
  • Pain in the joints
  • Cold and flu symptoms
  • Sweating

RARE SIDE EFFECTS –

  • Symptoms of stroke
  • Blood clots in the lungs
  • Blood clots in other parts of the body
  • Swelling around or on the breasts

DRUG INTERACTIONS –

  • Bexarotene
  • Carfilzomib
  • Lenalidomide
  • Pomalidomide
  • Thalidomide
  • Tranexamic Acid

Evista has major interactions with 6 different drugs.

MODERATE DRUG INTERACTIONS –

  • Colestipol
  • Estradiol
  • Estrone
  • Estropipate
  • Ospemifene
  • Quinestrol
  • Estramustine
  • Cholestyramine
  • Chlorotrianisene
  • Conestat alfa

Evista has moderate interactions with 17 different drugs.

PRECAUTIONS –

  • Provide the doctor with a detailed and accurate medical history prior to drug prescription. Notify especially in case of illnesses or conditions such as heart conditions, hypertension, cancer, smoking habits, blood clots, liver / kidney diseases, endometriosis, abnormal vaginal bleeding or high triglycerides in the body due to usage of estrogen.
  • Do not use this drug while pregnant, as it is meant for post-menopausal women.
  • Do not nurse while on drug course, as Evista may transfer through breast milk and harm the newborn.
  • The patient may need to stop taking the drug 3 days before a major surgery. Consult the surgeon with regards to the drug intake during the discussion of a surgery itself.
  • Cooperate with healthy diet plans and exercise schedules that will accompany the drug course, for effective results.
  • Self-examination and regular check-ups should take place every often, during drug course.
  • Inform the doctor of all the drugs being consumed so as to avoid severe drug interactions.
  • Do not sit still while traveling for long durations of time on drug course.
  • Take calcium supplements only as required (and as prescribed by a doctor) while on drug course.

WARNINGS –

  • Keep out of reach of children.
  • Doctors/Examiners must wear rubber gloves while handling the patient and this drug can pass through their bodily fluids.
  • This drug can increase risk of fatal stroke or blood clots in specific parts of the body.
  • In case of overdose, get medical help or contact a Poison Control Center immediately.

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