HEPARIN

10 Sep 2019

Generic Name : Generic Name : HEPARIN (INJECTION)

 

ABSTRACT –

Heparin is an anticoagulant in the injection form that is used to treat and prevent formation of blood clots that may occur due to certain medical conditions or procedures. Generally called a blood thinner, Heparin is used prior to surgery to prevent clots from forming while a surgical procedure is being conducted.

DOSAGE –

  • Heparin is to be taken as directed by the doctors. Consume this drug only as prescribed to avoid overdose or other harmful effects.
  • This drug is administered subcutaneously or injected as an infusion into a vein. Prepare injection only at the time of administering.
  • General Adult Dosage available:
    Injection – 1000units/mL

SIDE EFFECTS –

  • Mild pain, redness, irritation
  • Mild itching in the feet
  • Bruising at injection site

RARE SIDE EFFECTS:

  • Unusual amounts of bleeding
  • Severe pain/swelling within the stomach
  • Nausea
  • Unusual tiredness
  • Bleeding episodes
  • Severe fever
  • Runny nose
  • Skin changes at injection site
  • Signs of a blood clot

DRUG INTERACTIONS –

  • Alteplase
  • Ardeparin
  • Bivalirudin
  • Cangrelor
  • Caplacizumab
  • DanaparoidModafinil
  • Edoxaban
  • Ibrutinib
  • Ketorolac
  • Lepirudin
  • Mifepristone
  • Omacetaxine
  • Ponatinib
  • Reteplase
  • Streptokinase

Heparin has major interactions with 54 different drugs.

MODERATE DRUG INTERACTIONS –

  • Aliskiren
  • Bromfenac
  • Benazepril
  • Aspirin
  • Candesartan
  • Celecoxib
  • Desvelafaxine
  • Epoprostenol
  • Escitalopram
  • Ginseng
  • Glimepiride
  • Ibuprofen
  • Ketoprofen
  • Lisinopril
  • Naproxen
  • Olmesartan
  • Oxaprozin

Heparin has moderate interactions with 126 different drugs.

PRECAUTIONS –

  • Provide the doctor with a detailed and accurate medical history prior to drug prescription. Notify especially in case of illnesses and conditions such as kidney/liver disease, bacterial endocarditis, hypertensive blood pressure, blood clot disorders, intestinal disorder or the usage of a catheter.
  • Do not use this drug in case of an allergy to Heparin itself, in case of a history of low platelet count in reaction to heparin, general low platelet count or episodes of uncontrolled bleeding.
  • Notify a surgeon of drug use in case of any upcoming surgery or dental work.
  • Inform the doctor of all the drugs being consumed so as to avoid severe drug interactions. Notify especially in case of the use of a blood thinner such as warfarin or NSAIDs such as aspirin
  • Avoid nursing while on drug course.

WARNINGS –

  • Keep out of reach of children. A prefilled syringe is not to be used for children.
  • This drug can increase the risk of bleeding which may be life-threatening to the patient. Cooperate with regular tests to determine the time it takes for blood clots to occur. This drug can cause bleeding episodes during usage and for several weeks after drug course.
  • This drug should not be used to flush out an IV, so as to avoid fatal bleeding.
  • In case of overdose, get medical help or contact a Poison Control Center immediately. Overdose of this drug may lead to bloody urine, uncontrollable bleeding, or black stool.

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