11 Jun 2019
Generic Name : ALENDRONATE
Alendronate is a drug that is used to treat osteoporosis, gonadal failure and other conditions like steroid use. It is generally used when there is a potential risk of bone fracture due to osteoporosis. A bisphosphonate used to treat Paget’s bone disease, Alendronate inhibits bone resorption by working on osteoclasts to increase bone mineral density.
- Alendronate is to be taken as directed by the doctor.
- The general dosage is to be consumed once a day, or once a week. Consult your doctor regarding the intensity and frequency of drug consumption.
- Alendronate is to be ingested half an hour before consuming any food or water in the morning.
- The tablet is generally consumed whole along with a plain glass of water.
- General adult dosages available – Tablet – 35mg, 40mg, 70mg Effervescent tablet – 70mg/75mL
SIDE EFFECTS –
Diagnosis is usually recommended to –
- Decrease in serum calcium
- Decrease in serum phosphate
- Abdominal pains
- Severe joint pains or muscle pains
RARE SIDE EFFECTS:
- Upset stomachs
- Pain in the facial area
- Skin rashes
- Stomach bloating (gas)
- Severe Nausea
DRUG INTERACTIONS –
Alendronate has major interactions with two drugs.
MODERATE DRUG INTERACTIONS –
- Calcium acetate
- Magnesium lactate
Alendronate has moderate interactions with 220 different drugs
- Provide your doctor with a detailed and accurate medical history before drug prescription. Notify your doctor if you have indigestion, hypocalcaemia, kidney diseases, dental problems or problems that cause malabsorption.
- Brush and floss teeth regularly during course
- Do not consume Alendronate in case of an allergy or if you have low levels of calcium in your blood, or have problems with your esophageal tract.
- While using the effervescent tablet, notify your doctor of your diet – as this tablet contains a sizeable amount of sodium.
- Avoid Alendronate altogether if you find it difficult to stand up or sit upright 30 minutes after ingesting the medication.
- Do not smoke or consume large amounts of alcohol during course.
- Notify your doctor in case you use drugs like NSAIDs (Non-steroidal anti-inflammatory drugs) or aspirin.
- Notify a medical authority if symptoms like chest pains, heartburns, muscle spasms or unusual pains occur. These are signs or either esophageal problems or of new conditions centering the bones.
- Certain factors, combined with this drug can cause a condition called ‘osteonecrosis’ which involves severe pains in the jaw and dental area. Chemotherapy is a catalyst to osteonecrosis.
- Keep out of reach of children.
- In case of overdose, try not to vomit or lie down. Get medical help or contact a Poison Control Center immediately.