ARIPIPRAZOLE

14 Jun 2019

ABSTRACT –

Aripiprazole is a prescription drug used to treat schizophrenia and bipolar disorders. It is also used with some other medications for major depression disorders in adults and in children of age 6 or above who have Tourette’s disorder or Autism. It works by balancing dopamine and serotonin levels in the brain to improve thinking ability, mood and behavior. Aripiprazole belongs to a drug class known as atypical antipsychotics.

DOSAGE –

  • Aripiprazole has to be taken as directed by the doctor.
  • Adult and Pediatric dosages.
  • Tablet: 10mg, 15mg, 30mg

SIDE EFFECTS –

  • Anxiety
  • Constipation
  • Dizziness
  • Vomiting
  • Nausea
  • Headache
  • Insomnia
  • Muscle stiffness
  • Speaking difficulty
  • Restlessness
  • Stiffness of limbs
  • Drooling
  • Loss of balance control
  • Uncontrollable movements in the body
  • Muscle trembling

RARE SIDE EFFECTS:

  • High fever
  • High blood pressure
  • Low blood pressure
  • Excessive sweating
  • Seizures
  • Fainting

SHORT-TERM EFFECTS:

  • Irreversible tardive dyskinesia can develop.

LONG-TERM EFFECTS:

  • Prolonged use may cause blood pressure to drop.

DRUG INTERACTIONS –

  • Citalopram
  • Codeine
  • Cymbalta
  • Diazepam
  • Duloxetine
  • Fluoxetine
  • Lamictal
  • Lamotrigine
  • Latuda
  • Lexapro
  • Lithium Carbonate ER
  • Lyrica
  • Metoprolol
  • Norco
  • Olanzapine
Aripiprazole has moderate interactions with 1014 different drugs.

MILD INTERACTIONS OF ARIPIPRAZOLE ARE:

  • ProAir HFA
  • Prozac
  • Quetiapine
  • Sertraline
  • Symbicort
  • Trazodone

PRECAUTIONS –

  • All patients should be monitored closely.
  • Patients with major depressive disorder may experience their condition worsening.

PREGNANCY AND LACTATION WITH ARIPIPRAZOLE:

  • Use of Aripiprazole during pregnancy may harm the fetus as it might get transferred to breast milk.
  • Animal studies showed evidence of toxicity, including teratogenic effects.
  • Human studies are not available.
  • Discontinue the use of Aripiprazole if lactating and use cautionary measures.

WARNINGS –

  • Patients should be monitored closely.
  • Chances of risk increases with elderly patients.
  • In case of overdose get medical help or contact poison control immediately.

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