ATORVASTATIN

07 Aug 2019

Generic Name : ATORVASTATIN

ABSTRACT –

Atorvastatin is a medication drug that is generally used to treat high levels of cholesterol and as a preventive medication for strokes, heart conditions such as coronary heart disease as well as heart attacks in type-2 diabetic patients. Classified as a statin (HMH CoA reductase inhibitor), Atorvastin works by lowering the levels of low-density lipoprotein while increasing levels of high-density lipoprotein, thus keeping cholesterol levels healthy and under control.

DOSAGE –

    • Bisacodyl is to be taken as directed by the doctors. Dosage intensity may be subject to change.
    • The oral form of the drug is generally taken in its complete form at the same time once every day, with or without food.
    • This drug generally takes up to 2 weeks for improvement to be observed.
    • Atorvastatin is to be accompanied by a planned out schedule of healthy diets and appropriate amounts of exercise.
    • General Adult Dosage available:

Oral tablet – 10mg, 20mg, 40mg, 80mg

SIDE EFFECTS –

RARE SIDE EFFECTS:

  • Kidney failure
  • Difficulty urinating
  • Swellings
  • Jaundice
  • Loss of appetite

DRUG INTERACTIONS –

  • Amprenavir
  • Atazanavir
  • Boceprevir
  • Colchicine
  • Cyclosporine
  • Darunavir
  • Erythromycin
  • Fluconazole
  • Itraconazole
  • Ketoconazole
  • Lomitapide
  • Niacin
  • Ritonavir
  • Simeprevir
  • Telaprevir
  • Voriconazole

Atorvastin has major interactions with 40 different drugs.

MODERATE DRUG INTERACTIONS –

  • Aliskiren
  • Arithromycin
  • Butalbital
  • Bosentan
  • Cannabidiol
  • Efavirenz
  • Ivacaftor
  • Mitotane
  • Midazolam
  • Phenytoin
  • Rifabutin
  • Sarecycline
  • Tacrolimus

Atorvastin has moderate interactions with 209 different drugs.

PRECAUTIONS –

  • Provide the doctor with a detailed and accurate medical history prior to drug prescription. Notify especially in case of illnesses such as liver / kidney problems, muscle pain, diabetic conditions, thyroid disorder or alcohol abuse.
  • Do not consume this drug in case of an allergy to Atorvastatin itself or in case of severe liver disease.
  • Stop taking this drug temporarily in the occurrence of seizures, electrolyte imbalance, hypotension, severe illnesses or upcoming surgeries.
  • Cooperate with diet and exercise programs that are to be accompanied by the consumption of Atorvastatin. Avoid consuming foods that are high in cholesterol while on drug course.
  • Avoid consuming large amounts of alcohol while on drug course.
  • Avoid grapefruit while on drug course.
  • Provide a detailed drug history to the doctor, to avoid harmful drug interactions as some drugs in combination with Atorvastatin can cause severe muscle pain.
  • Do not consume this drug while pregnant or nursing, as it can cause harmful side effects.

WARNINGS –

  • Keep out of reach of children. This drug is for children and adults above the age of 10.
  • This drug, under certain conditions (such as hypothyroidism), can cause a rapid breakdown of skeletal muscle tissue – causing severe kidney failure.
  • In case of overdose, get medical help or contact a Poison Control Center immediately.

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