BONIVA

14 Jun 2019

Generic Name : IBANDRONATE (ORAL/INJECTION)

ABSTRACT –

Boniva is a bisphosphonate medication drug that is used in the prevention and treatment of osteoporosis in women after menopause. This drug helps in increasing bone mass, slows the breakdown of bones and prevents fractures by altering bone formation. It is classified as a ‘bisphosphonate’.

DOSAGE –

  • Boniva is to be taken as directed by the doctors.
  • The oral tablet is to be consumed whole once a month with a full glass of water, an hour before consuming food or beverages.
  • The injection is to be administered intravenously.
  • General Adult Dosage available:
  • Injection – 3mg, once in every three months (each dosage administered over 15-30 seconds)
    Oral tablet – 150mg per month

SIDE EFFECTS –

  • Blood in urine
  • Difficulty in urinating
  • Chest pain
  • Cough with mucus
  • Difficulty in breathing
  • Anxiety
  • Lower back pain
  • Irregular palpitations
  • Sneezing
  • Sore Throat
  • Fever
  • Diarrhea
  • Ear Congestion
  • Headache

RARE SIDE EFFECTS:

  • Severe heartburn
  • Pain under the ribs
  • Unusual pains in joints
  • Muscle spasms
  • Numbness
  • Difficulty in swallowing
  • Jaw pain

DRUG INTERACTIONS –

  • Cidofovi
  • Deferasirox
  • Diatrizoate
  • Etelcalcetide
  • Inotersen
  • Iodixanol
  • Metrizamide
  • Sirolimus
  • Tacrolimus
Boniva has major interactions with 41 different drugs.

MODERATE DRUG INTERACTIONS –

  • Adefovir
  • Amikacin
  • Aspirin
  • Bacitracin
  • Bromfenac
  • Celecoxib
  • Cyclosporine
  • Diclofenac
  • Entecavir
  • Fenoprofen
  • Gentamicin
  • Ibuprofen
  • Kaolin
  • Magaldrate
  • Rofecoxin
Boniva has moderate interactions with 253 different drugs.

PRECAUTIONS –

  • Provide your doctor with a detailed and accurate medical history before drug prescription. Notify especially in case of – hypocalcaemia, difficulties in swallowing, kidney diseases or dental problems.
  • Do not use Boniva in case of severe kidney diseases, low Calcium levels or problems with the esophagus.
  • Discontinue the drug in case you cannot stand upright an hour after administering the dosage.
  • Notify a doctor in case you are using aspirin or any NSAID (Non-steroidal Anti-inflammatory Drugs) before drug prescription.
  • After taking a tablet, do not recline or take any other medications within the following hour.
  • Maintain dental hygiene while on drug course.
  • Avoid smoking and drinking alcohol while on drug course.

WARNINGS –

  • Discontinue Boniva in case you have new or worsening pains, severe heartburns, muscle spasms or episodes of numbness or tingling. Contact your doctor immediately on observing such symptoms.
  • A risk of consuming this drug is that of osteoporosis in the jaw. Prolonged use of Boniva can bring about symptoms such as severe pains in the jaw, swollen gums or dental problems. Notify a doctor immediately in case this occurs.
  • Keep away from children.
  • In case of overdose, get medical help or contact a Poison Control Center immediately.

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