BOTOX

14 Jun 2019

ABSTRACT –

Botox is classified as a ‘skeletal muscle relaxant’ drug used to treat muscle-related and nerve-related several problems in adults, such as cervical dystonia, overactive bladder, chronic migraines and even certain eye muscle conditions and nerve disorders. This drug is made from the very bacterium that causes botulism, toxins of which block nerve activity in the muscles. Botox Cosmetic is popular for reducing the occurrence of wrinkles on the face, making it a go-to drug for doctors treating patients working in the modeling industry.

DOSAGE –

  • Botox is to be administered by medical authorities or trained professionals only.
  • Botox injections (in case of more than one) are given three months apart.
  • The units of Botox injections are specific to condition, method and intensity of condition. Only a medical authority is to decide the amount of units needed and method of administration.

SIDE EFFECTS –

  • Development of antibodies
  • Difficulty in swallowing
  • Increased sweating in areas other than the underarms
  • Bloody urine, difficulty in urinating, lower back pain (In case of overactive bladder)
  • Bruising on the eyelids, irritation or water eyes (In case of Blepharospasm)
  • Body aches, pains, chills, headache, congestion (In case of Cervical Dystonia)
RARE SIDE EFFECTS:
  • Difficulty with breathing
  • Trouble in speaking
  • Muscle fatigue

DRUG INTERACTIONS –

  • Amikacin
  • Atracurium
  • Doxacurium
  • Gentamicin
  • Kanamycin
  • Metocurin
  • Pancuronium
  • Rocuronium
  • Streptomycin
  • Tubocurarine
  • Vecuronium
  • Botox has major interactions with 24 different drugs..

    MODERATE DRUG INTERACTIONS –

  • AbobotulinumtoxinA
  • Amoxapine
  • Atropine
  • Azatadine
  • Baclofen
  • Belladonna
  • Biperiden
  • Chlorpheniramine
  • Clozapine
  • Flavoxate
  • Hyoscyamine
  • Loxapine
  • Maprotiline
  • Perphenazine
  • Promazine
Botox has moderate interactions with 356 different drugs.

PRECAUTIONS –

  • Botox is a drug that deals with symptoms temporarily. In certain cases, expecting symptoms to return within 2 or 3 weeks is natural.
  • Notify your doctor in case you take cold/allergy medicines, injection antibiotics, blood thinners or muscle relaxers prior to drug administration.
  • Notify your doctor in case there are infections in the area where Botox is to be applied.
  • Do not use Botox in case of – an allergy to the drug, current bladder infection or an infection in the area where it is to be administered.
  • Provide your doctor with a detailed and accurate medical history before drug prescription. Notify your doctor especially in case of – other injections, Lambert-Eaton syndrome, breathing disorders, difficulty in swallowing, bleeding problems, heart diseases or prior surgery.
  • Botox is made from donated human plasma and is required to be tested for viruses or other pathogens before being used on patient.
  • Consult a doctor before breastfeeding while using Botox as it may not be safe.
  • In case of eye treatment, consult a doctor with regards to the kind of protection the eye may need prior to injection. This could be in the form of lenses, eye drops or other devices.
  • In case of Botox treatment for extreme sweating, shave underarms 24 hours before injection.

WARNINGS –

  • Botox must not be used to treat tension headaches.
  • Botulinum toxin can spread to other places from where it was originally injected. In some cases, this can cause life threatening illnesses.
  • Botox can lead to impairment of vision and hearing. Avoid strenuous activity until safety is confirmed.
  • Do not ask for Botox from more than one healthcare provider as it can lead to overdose.
  • Contact your doctor immediately in case of the rare side effects mentioned above.
  • Do not use Botox to treat urinary infections in case patient cannot urinate at all.
  • Keep out of reach of children.
  • In case of overdose, get medical help or contact a Poison Control Center immediately. Signs of overdose include muscle weakness, difficulty swallowing or difficulty breathing.

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