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Generic Name : TICAGRELOR

ABSTRACT –

Brilinta is a drug that is generally used to prevent unwanted blood clots from occurring in patients who are recovering from a heart bypass surgery or a stent fixture. It is used in combination with drugs like aspirin to lower chances of stroke, heart problems or sudden death just after an attack. Classified as a ‘Platelet Aggression Inhibitor’, Brilinta works by preventing platelets in the blood stream from sticking together and causing an arterial block.

DOSAGE –

• Brilinta is to be taken as directed by the doctors. It is generally taken with Aspirin (proportionately). Consult a doctor as to how much aspirin should be taken with Brilinta.
• Oral tablet can be swallowed whole or crushed and consumed with water.
• General Adult Dosage available:
Loading dose – 180mg Maintenance dose – 90mg (twice a day, for one year)
• Maintenance dose may change after a year, in strength and intensity. Contact a medical authority for more details.

SIDE EFFECTS –

• Dyspnea
• Difficulty in breathing
• Tightness in the chest
• Bleeding

RARE SIDE EFFECTS:

• Swelling of breast in females
• Sore breasts in females
• Back pain
• Cough
• Diarrhea
• Nosebleeds
• Dizzy spells
• Easy bruising
• Fainting
• Discoloured urine or stool

DRUG INTERACTIONS –

• Acalabrutinib
• Apixaban
• Atazanavir
• Betrixaban
• Cobicisat
• Dalteparin
• Dalteparin
• Dasatinib
• Edoxaban
• Ibrutinib
• Ketocanazole
• Nelfinavir
• Omacetaxine
• Ponatinib
• Ritonavir
• Telaprevir
• Voriconazole

Brilinta has major interactions with 83 different drugs.

MODERATE DRUG INTERACTIONS –

• Alfentanil
• Aliskiren
• Alteplase
• Anagrelide
• Amlodipine
• Aspirin
• Bepridil
• Bivalirudin
• Bromfenac
• Butalbital
• Celecoxib
• Dicumarol
• Dofetilide
• Efavirenz
• Etravirine
• Ketoprofen
• Lomitapide
• Macitentan
• Midazolam
• Vorapaxar

Brilinta has moderate interactions with 384 different drugs.

PRECAUTIONS –

• Provide detailed and accurate medical before drug prescription. Notify doctor especially in case of – allergies to the drug, stroke, heart problems, cholesterol problems, excessive bleeding, stomach ulcers, liver diseases, kidney diseases, respiratory diseases or recent surgery.
• Notify drug history for medication to treat flu, cold or other allergies or even antifungal medication.
• Do not use Brilinta in case of bleeding trouble or a history of internal bleeding. Notify a doctor regarding such history.
• Avoid alcohol while on an aspirin course.
• Do not stop course unless advised to, even in case of bleeding. Consult your doctor regarding the bleeding and take measures as advised.
• Follow prescription and doctor’s advice carefully. In certain cases, such as before a surgical procedure, you may need to stop the course for a short period. Consult your doctor regarding the same, if and when necessary.

WARNINGS –

• Brilinta can lead to easy bleeding. Beware of bruising or cutting around patient’s skin. Keep patient away from hazardous objects.
• High amounts of aspirin can render Brilinta ineffective. Remember to follow doctor’s prescriptions regarding combination proportions.
• In case of internal bleeding, severe pains or bloody discharge, contact an emergency helpline immediately to avoid fatalities.
• Keep out of reach of children.
• In case of overdose, get medical help or contact a Poison Control Center immediately.