ABSTRACT – Celiac Disease or Coeliac Disease is also known as Celiac Sprue or Gluten Sensitive Enteropathy. It is...
Celiac Disease or Coeliac Disease is also known as Celiac Sprue or Gluten Sensitive Enteropathy. It is a chronic disorder affecting the small intestine. It is an immune reaction caused due to eating food containing gluten like wheat, barley etc. Over a period of time, this reaction damages the villi lining of small intestine and stops it from absorbing nutrients.
Glutenins and gliadins found in crops of the tribe Triticeae and Aveneae
Infant feeding practices
Pregnancy and child birth
SIGNS AND SYMPTOMS –
Bloating and gas
Abdominal pain and cramps
Nausea and vomiting
Malabsorption related symptoms:
Osteoporosis or osteomalacia
Copper and Zinc deficiency
Headache and fatigue
Effect on nervous system like balancing problem, cognitive impairment etc.
Growth failure or puberty delay
Immunoglobulin A (IgA) deficiency
Abnormal liver function
Other diagnostic tests like essential mineral and vitamin deficiency test, thyroid test etc.
Dual-energy X-ray Absorptiometry
Gluten free diet
Steroids or immunosuppressants for refractory disease
RISK FACTORS –
Other medical conditions like Diabetes, Down Syndrome, Addison’s disease etc
Feeding food containing gluten to infants after 6 months of age
If this condition is not treated, it may cause:
Infertility and miscarriage
Nervous system problems
People who do not respond to gluten free diet may suffer from:
Bacteria in small intestine
Refractory Celiac Disease
Difficulty in digesting sugar found in food items like honey and fruits
Irritable Bowel Syndrome (IBS)
Approximately 1 in 100 people suffer from this disease worldwide.
Indian and western culture have a high risk of Celiac disease than African, Japanese and Chinese culture.