Generic Name : AMANTADINE ABSTRACT – Amantadine is used in treatment of Parkinson’s disease and other conditions similar to...
Amantadine
Amantadine (trade name Symmetrel, by Endo Pharmaceuticals) is a medication that has U.S. Food and Drug Administration approval for use both as an antiviral and an antiparkinsonian medication. It is the organic compound 1-adamantylamine or 1-aminoadamantane, meaning it consists of an adamantane backbone that has an amino group substituted at one of the four methyne positions. Rimantadine is a closely related derivative of adamantane with similar biological properties.Apart from medical uses, this compound is useful as a building block in organic synthesis, allowing the insertion of an adamantyl group.Amantadine is used to treat Parkinson’s disease, as well as parkinsonism syndromes.[3] A 2003 Cochrane review concluded evidence was inadequate to support the use of amantadine for Parkinson’s disease