Generic Name : LUBIPROSTONE ABSTRACT – Amitiza is used in treating severe constipation caused due to unknown causes or...
Amitiza is a medication used in the management of chronic idiopathic constipation, predominantly irritable bowel syndrome-associated constipation in women and opioid-induced constipation.
It was initially approved by the U.S. Food and Drug Administration (FDA) in 2006 and recommended for use in the UK by the National Institute for Health and Care Excellence (NICE) in 2014. It is expensive as of 2017, with the cost to the NHS being £29.68 per 24 mg 28-cap pack as of April 2017.
Lubiprostone is also approved to treat opioid-induced constipation, in adults with chronic non-cancer pain. The effectiveness of lubiprostone has not been established in patients who are taking a diphenylheptane opioid (e.g., methadone).
Amitiza is approved to treat irritable bowel syndrome with constipation (IBS-C) in women 18 years of age and older.