ENTYVIO

17 Aug 2019

Generic Name : VEDOLIZUMAB

ABSTRACT –

Entyvio is a medication drug that works against inflammations. Classified as a selective immunosuppressant, Entyvio is generally used to treat ulcerative colitis or Crohn’s disease by reducing the requirement for the usage of steroids and controlling disease symptoms over long periods of time. Used in place of medication that was proven to be less effective, Entyvio works by reducing the chemicals in the body that cause specific types of inflammation.

DOSAGE –

    • Entyvio is to be taken as directed by the doctors. Consume this drug only as prescribed to avoid overdose or other harmful effects.
    • This drug is injected into the patient using an IV. It may take 30 minutes to complete a dosage.
    • This drug is given on a basic schedule between 2, 6 and 8 weeks every two months after the initial dose. Often, it takes several weeks for the full effects of this drug to be observed.
    • General Adult Dosage available:

IV Solution – 300mg

SIDE EFFECTS –

  • Fever
  • Sore throat
  • Flu
  • Pain in arms
  • Tiredness
  • Headache
  • Joint pain
  • Rashes or itching
  • Nausea
  • Vomiting

RARE SIDE EFFECTS:

  • Severe fever
  • Body aches
  • Severe nausea or vomiting
  • Oozing around the rectum
  • Cough
  • Pain while swallowing
  • Jaundice
  • Liver problems

DRUG INTERACTIONS –

  • Adalimumab
  • BCG vaccine
  • Etanercept
  • Fingolimod
  • Golimumab
  • Leflunomide
  • Natalizumab
  • Rotavirus vaccine
  • Siponimod
  • Yellow fever vaccine

Entyvio has major interactions with 26 different drugs.

MODERATE DRUG INTERACTIONS –

  • Alefacept
  • Anakinra
  • Azathioprine
  • Cholera vaccine
  • Denosumab
  • Efalizumab
  • Histoplasmin
  • Lyme disease vaccine
  • Omacetaxine
  • Plague vaccine
  • Rilonacept
  • Roflumilast
  • Tetanus toxoid
  • Ustekinumab

Entyvio has moderate interactions with 54 different drugs.

PRECAUTIONS –

  • Provide the doctor with a detailed and accurate medical history prior to drug prescription. Notify especially in case of illnesses such as any infection, tuberculosis, open wounds or sores, weakened immune systems or upcoming vaccines to be taken.
  • Do not consume this drug in case of an allergy to vedolizumab.
  • Inform the doctor of all the drugs being consumed so as to avoid severe drug interactions.
  • Avoid live vaccines or ‘killed-virus’ vaccines.

WARNINGS –

  • Keep out of reach of children. Do not give this drug to individuals under the age of 18 unless advised by a doctor.
  • In some cases, patients undergo a severe viral infection of the brain while using this drug. Report doctor as soon as symptoms such as vision loss or disorientation are observed.
  • In case of overdose, get medical help or contact a Poison Control Center immediately.

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