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Generic Name : RALOXIFENE

ABSTRACT –

Evista is a medication drug that is used to treat osteoporosis and prevent invasive breast cancer in post-menopausal women. This drug is classified as a selective estrogen receptor modulator that influences the manner in which bone formation/breakdown occurs in the body, thus reducing the rate at which bone tissue loss (osteoporosis) occurs. Evista is also an antineoplastic agent.

DOSAGE –

• Evista is to be taken as directed by the doctors. Consume this drug only as prescribed to avoid overdose or other harmful effects.
• This drug is to be taken at the same time every day with/without food.
• General Adult Dosage available:

Oral – 60mg per day

SIDE EFFECTS –

• Cramps in the leg
• Swelling in the limbs
• Hot flashes
• Pain in the joints
• Cold and flu symptoms
• Sweating

RARE SIDE EFFECTS –

• Symptoms of stroke
• Blood clots in the lungs
• Blood clots in other parts of the body
• Swelling around or on the breasts

DRUG INTERACTIONS –

• Bexarotene
• Carfilzomib
• Lenalidomide
• Pomalidomide
• Thalidomide
• Tranexamic Acid

Evista has major interactions with 6 different drugs.

MODERATE DRUG INTERACTIONS –

• Colestipol
• Estradiol
• Estrone
• Estropipate
• Ospemifene
• Quinestrol
• Estramustine
• Cholestyramine
• Chlorotrianisene
• Conestat alfa

Evista has moderate interactions with 17 different drugs.

PRECAUTIONS –

• Provide the doctor with a detailed and accurate medical history prior to drug prescription. Notify especially in case of illnesses or conditions such as heart conditions, hypertension, cancer, smoking habits, blood clots, liver / kidney diseases, endometriosis, abnormal vaginal bleeding or high triglycerides in the body due to usage of estrogen.
• Do not use this drug while pregnant, as it is meant for post-menopausal women.
• Do not nurse while on drug course, as Evista may transfer through breast milk and harm the newborn.
• The patient may need to stop taking the drug 3 days before a major surgery. Consult the surgeon with regards to the drug intake during the discussion of a surgery itself.
• Cooperate with healthy diet plans and exercise schedules that will accompany the drug course, for effective results.
• Self-examination and regular check-ups should take place every often, during drug course.
• Inform the doctor of all the drugs being consumed so as to avoid severe drug interactions.
• Do not sit still while traveling for long durations of time on drug course.
• Take calcium supplements only as required (and as prescribed by a doctor) while on drug course.

WARNINGS –

• Keep out of reach of children.
• Doctors/Examiners must wear rubber gloves while handling the patient and this drug can pass through their bodily fluids.
• This drug can increase risk of fatal stroke or blood clots in specific parts of the body.
• In case of overdose, get medical help or contact a Poison Control Center immediately.