FOSAMAX

27 Aug 2019

Generic Name : ALENDRONATE

ABSTRACT –

This medication is a type of bisphosphonate which results in altering bone formation and helps to prevent bone loss. The drug also helps to prevent bone fractures. This drug is used by both males and females for treating osteoporosis which can be the result of steroids and menopause. This drug is also used to enhance bone mass in males.

DOSAGE –

  • Fosamax has to be taken as directed by the doctors
  • Adult dosages:
    Tablet: 5 mg, 10 mg, 35 mg, 40 mg
    Recommended dose- 10 mg daily

SIDE EFFECTS –

  • Abdominal cramps
  • Loosening of the skin
  • Bloating or swelling in the face, arms, hands, lower legs or feet
  • Joint or muscle pain
  • Chest pain
  • Chills
  • Shortness of breath
  • Sore throat
  • Convulsions
  • Cough
  • Diarrhea
  • Irregular heartbeats
  • Itching
  • Joint pain
  • Mouth ulcers
  • Swollen joints
  • Difficulty with breathing
  • Heartburn
  • Unusual weakness
  • Unusual weight gain or loss
  • Vomiting

RARE SIDE EFFECTS –

  • Difficulty with swallowing
  • Skin rashes
  • Muscle ache and cramps
  • Heartburn
  • Painful irritation in esophagus
  • Numbness in mouth, fingertips or feet
  • Numbness
  • Rapid weight gain
  • Red skin lesions, often with centered purple
  • Red and irritated eyes

DRUG INTERACTIONS –

  • Deferasirox
  • Etelcalcetide

Fosamax has major interactions with 2 different drugs.

MODERATE DRUG INTERACTIONS –

  • Attapulgite
  • Bevacizumab
  • Bromfenac
  • Furosemide
  • Gentamicin
  • <liTorsemide

  • Valdecoxib
  • Zinc acetate
  • Oxaprozin
  • Ketorolac
  • Lanthanum carbonate
  • Magaldrate
  • Heme iron polypeptide
  • Bumetanide
  • Calcium acetate
  • Ethacrynic acid
  • Etodolac
  • Fosamax has moderate interactions with 96 different drugs.

    PRECAUTIONS –

    • The medication should not be used in case patient has low levels of calcium in body or problem with esophagus
    • Use of this drug should be stopped if the patient is unable to sit upright for minimum 30 minutes after consuming the drug.
    • Be careful as this drug might also result in bone loss in the jaw or femur fractures in rare cases.
    • This drug contains inactive ingredients which may result in allergic reactions. So a pharmacist must be consulted before consuming it.
    • It is of utmost necessity to discuss any medical history related to kidney disease, stomach problems, low calcium levels, malabsorption, dental problems, or trouble swallowing.
    • The use of this drug is not recommended in children

    PREGNANCY AND LACTATION WITH FOSAMAX:

    • Use of Fosamax in pregnancy may be acceptable only if the benefits exceed the risks involved
    • Studies in animal pregnancy have shown adverse effects on fetus. But no adequate studies have been found in humans to access the damage involved.
    • It is not known if Fosamax transfers into breast milk. Preferable precautions must be taken during breast feeding.

    WARNINGS –

    • Use of this medicine might result in adverse symptoms like severe chest pain, worsening heartburn, or pain in esophagus while swallowing. If this happens, call your doctor immediately.
    • Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.

    The Ultimate Pharma Guide

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