GLIPIZIDE

26 Aug 2019

Generic Name : GLIPIZIDE

ABSTRACT –

Glipizide is classified under the drug category ‘sulfonylureas’. It is an anti-diabetic drug that is used to improve the condition of blood sugar control in patients that suffer from type 2 diabetes mellitus. As an oral diabetes drug, Glipizide is generally accompanied by appropriate diet and exercise plans. This drug works by enforcing the pancreas to produce more insulin and thus controlling blood sugar levels.

DOSAGE –

  • Glipizide is to be taken as directed by the doctors. Consume this drug only as prescribed to avoid overdose or other harmful effects.
  • This drug is taken once a day half an hour before breakfast.
  • The regular tablet is to be swallowed whole without crushing or breaking.
  • General Adult Dosage available:
  • Oral – 5mg, 10mg, 2.5mg

SIDE EFFECTS –

  • Diarrhea
  • Constipation
  • Passing of gas
  • Tremors
  • Skin rashes/skin irritation

RARE SIDE EFFECTS –

  • Headache
  • Sweating
  • Rapid palpitations
  • Dizziness
  • Nausea
  • Hunger
  • Restlessness

DRUG INTERACTIONS –

  • Ciprofloxacin
  • Delafloxacin
  • Enoxacin
  • Fluconazole
  • Gemifloxacin
  • Grepafloxacin
  • Gatifloxacin
  • Lomefloxacin
  • Ofloxacin
  • Sparfloxacin
  • Trovafloxacin
  • Voriconazole

Glipizide has major interactions with 19 different drugs.

MODERATE DRUG INTERACTIONS –

  • Acebutolol
  • Albuterol
  • Amoxapine
  • Aspirin
  • Atenolol
  • Atazanavir
  • Benazepril
  • Bosentan
  • Brigatinib
  • Citalopram
  • Danazol
  • Diazoxide
  • Ephedrine
  • Estrone
  • Furosemide

Glipizide has moderate interactions with 357 different drugs.

PRECAUTIONS –

  • Provide the doctor with a detailed and accurate medical history prior to drug prescription. Notify especially in case of illnesses and conditions such as chronic diarrhea, liver/kidney disease, or a G6PD deficiency.
  • Do not use this drug in case of an allergy to Glipizide itself or in case of diabetic ketoacidosis.
  • Inform the doctor of all the drugs being consumed so as to avoid severe drug interactions.
  • This drug can harm a baby in case of nursing period or pregnancy. Consult a doctor as to the use of this drug during feeding and gestation. It is advised to stop consuming this drug for at least 2 weeks prior to due date of delivery.
  • Avoid alcohol while on drug course.
  • Cooperate with regular blood sugar tests to ensure regular health.

WARNINGS –

  • Keep out of reach of children. Glipizide is not approved for anyone under the age of 18.
  • In case of severe hypoglycemia, use a glucagon kit or consume a fast-acting source of sugar for re-energization.
  • In case of overdose, get medical help or contact a Poison Control Center immediately. Overdose can cause severe hypoglycemia.

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