INDOMETHACIN

22 Nov 2019

Generic Name :INDOMETHACIN

ABSTRACT-

Indomethacin is used to treat swelling, pain, shoulder and joint inflexibility caused due to moderate to severe osteoarthritis, rheumatoid arthritis, gout, or spondylitis. It is a NSAID (Nonsteroidal Anti-Inflammatory Drug) which is also used to treat muscle and joint pain caused by bursitis or tendinitis.

DOSAGE–

  • Indomethacin is to be taken as directed by the doctors. Consume this drug only as prescribed to avoid overdose or other harmful effects.
  • Dosages: 25 mg; 50 mg; 75 mg; 25 mg/5 mL; 1 mg; 20 mg and 40 mg

SIDE EFFECTS–

  • Acidity
  • Diarhhea
  • Nausea
  • Burping
  • Indigestion
  • Stomach pain

RARE SIDE EFFECTS:

  • Back pain
  • Blood in stools
  • Itching
  • Numbness in the hands
  • Confusion
  • Pale skin
  • Dizziness
  • Dry skin
  • Hair loss
  • Headache
  • Ulcers

DRUG INTERACTIONS–

  • Adefovir
  • Cabozantinib
  • Desirudin
  • Betrixaban
  • Fondaparinux
  • Ketorolac
  • Lomitapide
  • Prasugrel
  • Tacrolimus
  • Warfarin
  • Vorapaxar

Indomethacin has major interactions with 67 different drugs.

MODERATE DRUG INTERACTIONS –

  • Alendronate
  • Betaxolol
  • Celecoxib
  • Daclizumab
  • Esmolol
  • Glucagon
  • Fenoprofen
  • Iloprost
  • Meloxicam
  • Nitisinone
  • Probenecid
  • Quinapril
  • Rucaparib
  • Telmisartan
  • Zidovudine

Indomethasin has moderate interactions with 248 different drugs.

PRECAUTIONS–

  • Provide the doctor with a detailed and accurate medical history prior to drug prescription. Notify especially in case of illnesses and conditions related to heart, high BP, stomach ulcers, liver or kidney diseases.
  • Children below 14 years of age are not recommended to use this drug.
  • Do not use this drug in case of an allergy to Indomethacin itself or Aspirin.
  • Do not nurse while on drug course as it can affect the unborn baby.
  • Use necessary precautions and birth control measures to prevent pregnancy during the drug course.

WARNINGS–

  • Indomethacin can increase the chances of fatal heart attack or stroke hence it is not at all recommended before or after heart bypass surgery.
  • It can also result in intestinal or stomach bleeding in older adults. Consult doctor on timely basis.
  • Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.

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