Treatable mechanism found in Schizophrenic Patients

08 Apr 2019

Researchers at Karolinska Institute, Sweden and Massachusetts General Hospital have been successful in creating models of the human cells that show the degradation of neural connections in the brains of patients of Schizophrenia. For unclear reasons, it has been proven that Schizophrenic patients have lesser neurons connections in the brain than the normal. In the late teens, intensive synaptic pruning caused adolescents to succumb to schizophrenia. This synaptic pruning occurs due to two reason. First: disrupted function of microglia and Second: aberrations in the synapses. These have been proven by various experiments. It has also been proven that the antibiotic minocycline, treated with microglia can inhibit pruning and hence assist prevention of schizophrenia.

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